The Coalition membership of physical scientists is drawn from nearly all states in the United States. This constitutes an effective network of scientists that advocates as informed citizen-scientists for steps to reduce the nuclear threat. The Coalition leadership is composed of The Steering Committee, The Project Team, The Advisory Committee, and a Policy and Communications Coordinator. It partners with the Arms Control Association (ACA) and The Princeton Program on Science and Global Security.

The Steering Committee oversees and guides all aspects of Coalition activity. The current members of this committee are Laura Grego, Daryl G. Kimball, Frederick K. Lamb, Zia Mian, Stewart Prager, and Frank von Hippel.

The Coalition Project Team consists of physical scientists who are experts on nuclear arms control issues. The Project Team members inform the physics community about the threat of nuclear weapons through in-person or online educational sessions referred to as Colloquia. They also introduce physicists to the Coalition and help foster local and national advocacy. We have so far held colloquia at institutions all across the United States, Canada, and beyond.